Associate Director CMC – Esobiotec - AstraZeneca group

Do you thrive in innovative environments and are committed to advancing transformative therapies ?

As a proud new member of the AstraZeneca family, Esobiotec continues to set new standards in pioneering biotechnological research. With a shared vision to transform the future of medicine, our partnership leverages AstraZeneca’s global reach and rich heritage in scientific innovation, amplifying Esobiotec’s unique culture of creativity and breakthrough advances in cell-based therapies and immunology. At Esobiotec, now backed by the resources and expertise of one of the world’s leading biopharmaceutical companies, you’ll find a dynamic, collaborative environment where scientific passion drives real-world impact. Be part of a team where your work will contribute to shaping the next generation of life-changing treatments and help us push the boundaries of science to improve patients’ lives worldwide.

We are looking for an inspiring CMC leader to drive innovation in the manufacturing and development of our pioneering lentiviral therapies. Join our mission-driven team and help shape the future of cell and gene therapy with your expertise in process development, analytics, and regulatory strategy. We value diverse perspectives and a collaborative, growth-minded approach.

What You’ll Do

• Lead and coordinate a talented CMC team responsible for multiple manufacturing campaigns supporting Investigator Initiated Trials (IIT), IND-enabling studies, and clinical programs for EsoBiotec’s lentiviral products.
• Design, optimize, and scale up upstream and downstream manufacturing processes, guiding products from research through GMP-readiness.
• Champion the development of robust analytical methods and ensure excellence in process control and product characterization.
• Serve as a strategic partner to Regulatory Affairs, helping to shape CMC strategies and prepare high-quality regulatory submissions.
• Oversee pre-GMP and GMP vector manufacturing and testing at external CDMOs, ensuring quality, timelines, and cost-effectiveness.
• Review and approve manufacturing and analytical plans and reports, both internally and from partner organizations, maintaining program timelines and budgets.
• Recruit, mentor, and develop a high-performing, diverse team, fostering scientific rigor and a culture of continuous improvement.
• Direct technical transfer activities to CDMOs, ensuring seamless communication and execution at every step.

What You’ll Bring

Desirable skills :

At AstraZeneca Group, we are committed to pushing the boundaries of science to transform the lives of patients living with cancer. Our diverse team collaborates seamlessly, drawing on collective wisdom from across the globe to tackle the toughest medical challenges. With one of the broadest Oncology pipelines in the industry, we offer unparalleled opportunities to work with novel drugs and innovative approaches. Empowered by courage and curiosity, we take smart risks and challenge norms to make a meaningful difference in patient outcomes.

So, what is next :

If you're ready to shape the future of gene therapy and lead high-impact teams in a vibrant, mission-driven company, we would love to hear from you!

Welcome with your application, in English , latest  by the 15 / 07 / 2025

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Date Posted

01-juli-2025

Closing Date

15-juli-2025